diff --git a/sentry_sdk/integrations/openai.py b/sentry_sdk/integrations/openai.py
index 99a50fcd0c..1fbc22021e 100644
--- a/sentry_sdk/integrations/openai.py
+++ b/sentry_sdk/integrations/openai.py
@@ -301,7 +301,7 @@ def _calculate_responses_token_usage(
         if streaming_message_responses is not None:
             for message in streaming_message_responses:
                 output_tokens += count_tokens(message)
-        elif hasattr(response, "output"):
+        elif hasattr(response, "output") and isinstance(response.output, list):
             for output_item in response.output:
                 if hasattr(output_item, "content"):
                     for content_item in output_item.content:
@@ -711,7 +711,9 @@ def _set_common_output_data(
             "tool": [],
         }
 
-        if has_data_collection_enabled(client.options):
+        if has_data_collection_enabled(client.options) and isinstance(
+            response.output, list
+        ):
             record_outputs = client.options["data_collection"]["gen_ai"]["outputs"]
 
             if record_outputs:
@@ -741,7 +743,11 @@ def _set_common_output_data(
                         span, SPANDATA.GEN_AI_RESPONSE_TEXT, output_messages["response"]
                     )
 
-        elif should_send_default_pii() and integration.include_prompts:
+        elif (
+            should_send_default_pii()
+            and integration.include_prompts
+            and isinstance(response.output, list)
+        ):
             for output in response.output:
                 if output.type == "function_call":
                     output_messages["tool"].append(output.dict())