diff --git a/Dockerfile b/Dockerfile
index e9f73d1..0964b23 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -1,4 +1,4 @@
-FROM continuumio/miniconda3:24.1.2-0 AS nmrkit-ms
+FROM continuumio/miniconda3:25.3.1-1 AS nmrkit-ms
 ARG TARGETARCH=amd64
 
 ENV PYTHON_VERSION=3.10
@@ -24,8 +24,13 @@ RUN apt-get update && \
 
 RUN apt-get update && apt-get -y install docker.io
 
-RUN conda install -c conda-forge python>=PYTHON_VERSION
-RUN conda install -c conda-forge openbabel>=OPENBABEL_VERSION
+RUN conda config --remove-key channels && \
+    conda config --add channels conda-forge && \
+    conda config --set channel_priority strict
+
+RUN conda install -y \
+    "python=${PYTHON_VERSION}" \
+    "openbabel>=${OPENBABEL_VERSION}"
 
 RUN pip3 install rdkit
 
@@ -51,8 +56,11 @@ RUN python3 -m pip install uvicorn[standard]
 
 COPY ./app /code/app
 
-RUN curl -sL https://deb.nodesource.com/setup_current.x | bash -
-RUN apt-get install -y nodejs
+# Download the setup script first so a failure fails the build instead of being masked by the pipe
+RUN curl -fsSL https://deb.nodesource.com/setup_24.x -o /tmp/nodesource_setup.sh && \
+    bash /tmp/nodesource_setup.sh && \
+    apt-get install -y nodejs && \
+    rm -rf /var/lib/apt/lists/* /tmp/nodesource_setup.sh
 RUN npm install -g npm@latest
 
 RUN npm install -g /code/app/scripts/nmr-cli